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$2,800,000
21207553 MLS
PRIME 11.88-Acre Opportunity in the Heart of Denison! This exceptional tract offers approximately 400 feet of Highway 75 frontage, creating outstanding visibility and access for future development. Perfectly positioned at the corner of Highway 75 and Stafford Drive, the property is located in a rapidly growing corridor with planned TXDOT improvements that include a future on-ramp and off-ramp approx at Stafford, further enhancing accessibility and long-term value. With its high-traffic location and excellent exposure, this property presents a remarkable opportunity for commercial, mixed-use, or investment development. Adding to its appeal, the tract is located within the highly sought-after Hyde Park Elementary School zone, making it an attractive location for a variety of potential uses. Whether you’re a developer, investor, or visionary entrepreneur, this property offers the space, location, and momentum to bring your next project to life. Opportunities like this, large acreage with prime highway frontage in Denison’s expanding growth corridor, are increasingly RARE. Secure your place in one of the area’s most promising development locations today.

000 Stafford Dr, Denison

$2,700,000
21129574 MLS
This remarkable 36,000 SF building in downtown Denison, built in the 1890s, offers an unmatched opportunity for a buyer to utilize a highly versatile and historic downtown asset. The four-story building is currently set up for a full-service TV marketing production business with multiple edit suites, recording studios, and a green screen room. The building includes over 45 spacious move-in ready offices, along with Fully restored men's and women's restrooms are located on each floor, and an elevator in the lobby services all four stories. a 5,500 SF luxury penthouse apartment located on the third floor that includes 4 bedrooms and 5 bathrooms, two wet bars, a fully functional kitchen, and a covered patio. The sale also includes two downtown parking lots, one of which was repaved in the last three years and offers 29 parking spaces on Main Street. The property is within walking distance to several restaurants, retail, and offices. The Denison Development Alliance and the City of Denison offer incentives that may benefit this building by helping attract targeted businesses and support site improvements, development, and renovation. Additionally, the City of Denison is in Phase 2 of a downtown project improving streetscapes, accessibility, and public spaces.. Downtown Denison is a recent winner of the 2025 Great American Main Street Award and thrives as a hub for community and commerce.

531 W Main St, Denison

$1,599,999
21104922 MLS
Prime ±25 acres along FM 691 inside Denison city limits, with city water and sewer access and exceptional dual frontage on FM 691 and Theresa Dr. FM 691 is a key east-west corridor between US-75 and Texoma Parkway, serving the Sherman–Denison trade area. The site sits in the heart of the region’s medical and hospitality growth—Texoma Medical Center approx. 414 beds; ~88,000 patients treated anchors the US-75 and FM 691 intersection, with new medical offices and services nearby. Hilton Garden Inn and the Texoma Event Center at US-75 and FM 691 provide a regional destination for conferences and community events. With excellent visibility, utilities, and multiple access points, this tract is ideal for medical or office, retail, hospitality, or mixed-use development - subject to city approvals. Buyer to verify all information, including utilities, zoning, and dimensions.

000 Grayson Dr, Denison

$5,635,903
21098618 MLS
Prime +-39.81 acre corner tracts located at Highway 120 and FM 131 in Denison, Texas. This property offers exceptional potential for development in one of North Texas’ fastest-growing areas. Currently zoned Agricultural with access to city utilities, the site provides a flexible opportunity for residential, commercial, or mixed-use projects subject to rezoning. Its strategic location offers excellent visibility and accessibility, with frontage along two major roadways and proximity to downtown Denison, Highway 75, and local amenities. The property sits just minutes from the proposed North Texas Tollway extension connecting Dallas to Denison, positioning it directly in the path of future growth. Whether held as a long-term investment or advanced for immediate development, these tracts represent one of the area’s most promising opportunities for expansion. Buyer and buyer’s agent to verify acreage, boundaries, zoning, utility availability, and all development requirements with the City of Denison.

TBD Fm-131, Denison

$1,800,000
21023523 MLS
Rare opportunity to purchase a long-established, fully operational daycare business with real estate in the heart of Denison, Texas. Kiddie Kampus has been family owned and operated for over 50 years and has built a trusted name in the community. The main location on Lillis Lane is licensed for 127 children, including 7 infants, and typically runs with 80–100 kids enrolled at any given time. It’s a true turnkey setup with five classrooms, a dedicated nursery, a full service kitchen and dining area, office space, three bathrooms, laundry and an oversized outdoor playground which allows plenty of room for expansion. The center serves children from infants through age 12 and offers after-school programs with transportation provided to all Denison ISD schools. Three vehicles—a full-size bus, a cutaway bus, and a van—are included. Kiddie Kampus holds a 4-star Texas Rising Star certification (the highest level) and has been voted “Best in Texoma” multiple years, reflecting its excellent reputation and consistent demand in this market. The location is ideally situated near elementary and middle schools and within a growing residential area supported by major employers like Texoma Medical Center, Ruiz Foods, and the new $30B Texas Instruments facility in nearby Sherman. Denison and greater Grayson County continue to see explosive population growth, making quality childcare more in demand than ever.  Also available for purchase is a second, vacant daycare facility at 1500 & 1506 W. Crawford St not far from this one offering room to expand or open a second location under the same brand. This is a completely optional purchase and is not a requirement to purchase the daycare business with Lillis Lane building location. See additional flyer for the 1500 W. Crawford building for more information as well as the MLS listing. MLS# 20793728.

117 N Lillis Ln, Denison

$1,350,000
21015991 MLS
Welcome to the crown jewel of Thompson Heights! Lot 2A-1 offers 2.83 acres of pristine lakefront property with deeded ownership to the water's edge, a rare find on Lake Texoma. Enjoy two private 50-ft boat slips in a brand-new, fully equipped boathouse with water and power. This estate-sized lot provides endless possibilities for your custom lake home with panoramic views and total privacy. Located just minutes from Eisenhower State Park, marinas, and the highly anticipated Margaritaville!. Underground utilities and paved access already in place. Live lake life without compromise. Highlights: 2.83 Acres 2 Deeded Boat Slips Private, Build-Ready Estate Lot Panoramic Lake Views Paved Access + Electricity Ownership to Shoreline (No Corps Buffer) Call your favorite REALTOR® today!

Lot 2A-1 Thompson Heights, Denison

$1,200,000
3 Beds 3 Baths 20938391 MLS
Prime 8.8-Acre Development Opportunity in Denison, TX Located in one of Denison’s fastest-growing corridors near HWY 75, 3220 Randall Lake Rd presents a rare chance to invest in the path of progress. This 8.8-acre tract is currently zoned agricultural and benefits from an ag exemption, offering valuable tax advantages while development plans are underway. City water, sewer, and electric are already on site, making this property truly development ready. A well-maintained 3,000 sq ft home is also located on the property, offering flexible use as an office, event venue, sales center, or staff housing. Self-storage and retail developments are already moving dirt and preparing to build adjacent to the property, further boosting its visibility and commercial potential. Surrounded by new and upcoming single-family communities, retail developments, and major projects —including the highly anticipated Margaritaville Resort—this property offers strong future demand. Whether you're planning retail, mixed-use, hospitality, or storage, this land is ideally positioned for long-term success in Denison’s booming commercial landscape.

3220 Randell Lake Rd, Denison

$1,200,000
20709794 MLS
Positioned directly across from the fully restored Katy Depot, this iconic property represents a rare opportunity to acquire a cornerstone asset in the heart of Historic Downtown Denison. This two-story, 19,200 SF structure (plus 9600 sqft potential basementl) offers expansive open spans and exceptional ceiling heights, creating a highly flexible canvas for adaptive reuse. The property is ideally suited for a variety of high-impact concepts including an event and entertainment venue, multi-tenant restaurant destination, boutique office environment, or residential loft conversion. A significant value-add component exists with the inclusion of a basement level, offering the potential to expand the building by an additional ±9,000 square feet. The asset also features a private parking lot with approximately 20 dedicated spaces—an increasingly rare amenity in downtown environments. Located within an Opportunity Zone and eligible for Historic Tax Credits, the property presents a compelling basis for a tax-advantaged redevelopment strategy. Ownership will also benefit from proximity to Denison’s ongoing downtown revitalization initiatives, with potential access to local incentive programs. Surrounded by established destinations including Stafford House, 34 Chophouse, and Landon Winery, the property sits within walking distance of Denison’s most active and growing hospitality corridor.

114 N Houston Ave, Denison

Listings provided by North Texas Real Estate Information Systems (NTREIS). Listing data has been deemed reliable but is not guaranteed to be accurate by the MLS.

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